Levamlodipine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

氨氯地平是一种合成的二氢吡啶和钙通道阻滞剂，具有抗高血压和抗心绞痛特性。

Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.

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Levamlodipine | S-Amlodipine |

GPCR/G Protein

Calcium Channel

Calcium Channel

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103129-82-4

408.88

C20H25N2O5Cl

>98% (HPLC)

DMSO: 10 mM

O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC

3-ethyl 5-methyl (S)-2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

(-20℃)

With Ice Pack

≥ 2 years