Levamlodipine ( Levamlodipine | S-Amlodipine | )

产品货号. M10152 CAS No. 103129-82-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Levamlodipine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

氨氯地平是一种合成的二氢吡啶和钙通道阻滞剂，具有抗高血压和抗心绞痛特性。
产品描述

Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
体外实验

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体内实验

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同义词

Levamlodipine | S-Amlodipine |
通路

GPCR/G Protein
靶点

Calcium Channel
受体

Calcium Channel
研究领域

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适应症

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CAS Number

103129-82-4
分子量

408.88
分子式

C20H25N2O5Cl
纯度

>98% (HPLC)
溶解度

DMSO: 10 mM
SMILES

O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC
化学全称

3-ethyl 5-methyl (S)-2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

1.Gui H, et al. CNS Neurosci Ther. 2013 Mar;19(3):178-82.

计算器

产品手册

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