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CK-37
CAS No. 1001478-90-5
CK-37 ( ChoK-α inhibitor CK37 )
产品货号. M10017 CAS No. 1001478-90-5
一种有效、特异性、竞争性的胆碱激酶-α (Chok-α) 抑制剂，靶向胆碱结合位点。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥9858 | 有现货 |
|
| 50MG | ￥12834 | 有现货 |
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| 100MG | ￥15750 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CK-37
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述一种有效、特异性、竞争性的胆碱激酶-α (Chok-α) 抑制剂，靶向胆碱结合位点。
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产品描述A potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site; significantly increases LC3II expression in MCF-7 and MCF-7/TAM cells, increases the size and number of autophagosome, causes MCF-7 and MCF-7/TAM cells to a slight increase in p62; suppresses MAPK and PI3K/AKT signaling, disrupts actin cytoskeletal organization, and reduces plasma membrane ruffling; significantly decreases tumor growth in a lung tumor xenograft mouse model, suppresses tumor phosphocholine, and diminishes activating phosphorylations of ERK and AKT in vivo.
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体外实验——
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体内实验——
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同义词ChoK-α inhibitor CK37
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通路Others
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靶点ChoK
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受体ChoK
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研究领域——
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适应症——
化学信息
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CAS Number1001478-90-5
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分子量366.483
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分子式C20H22N4OS
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纯度>98% (HPLC)
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溶解度——
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SMILESCCC1=CC=C(C=C1)C2=NC(=NN2)SCC(=O)NC3=CC(=CC(=C3)C)C
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化学全称N-(3,5-dimethylphenyl)-2-[[5-(4-ethylphenyl)-1H-1,2,4-triazol-3-yl]sulfanyl] acetamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Clem BF, et al. Oncogene. 2011 Jul 28;30(30):3370-80.
2. Kim HS, et al. PLoS One. 2015 Oct 23;10(10):e0141110.
3. Wong MT, et al. J Virol. 2016 Sep 29;90(20):9075-95.
