β-Cembrenediol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation.

β-Cembrenediol is a potent and orally active anticancer agent. β-Cembrenediol shows phytotoxic activities. β-Cembrenediol reduces the migration and colony formation. β-Cembrenediol decreases the protein expression of TDO2, IDO1. β-Cembrenediol has the potential for the research of prostate cancer.

β-Cembrenediol (15 mg/kg; p.o.; daily for 8 weeks) 对前列腺癌小鼠表现出抗肿瘤活性。Animal Model:Male athymic nude mice (PC-3M PC cells)Dosage:15 mg/kg Administration:P.o.; daily for 8 weeks Result:Significantly suppressed the development, extended the latency, and delayed the onset of the locoregional PC-3M cell tumor recurrence, reduced mice plasma total prostate-specific antigen and plasma kynurenine level.

β-Cembrenediol (25、50、100、200 μg/mL) 以剂量依赖性方式抑制生菜幼苗茎长和根长。β-Cembrenediol (0、0.2、0.5、1、5、10 μM) 以剂量依赖性方式减少迁移和菌落形成。β-Cembrenediol (5、10、20 μM；48 小时) 以剂量依赖性方式降低 TDO2、IDO1 的蛋白质表达。Western Blot Analysis Cell Line:PC-3M cells Concentration:5, 10, 20 μM Incubation Time:48 h Result:Decreased the protein expression of TDO2, IDO1 in a dose-dependent manner.

西柏三烯醇

Others

Other Targets

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57605-81-9

306.49

C20H34O2

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years