021-51111890
购物车（）
sales@molnova.cn
YM-750
CAS No. 138046-43-2
YM-750 ( YM 750 | YM-750 )
产品货号. M27744 CAS No. 138046-43-2
YM-750 是一种有效的酰基辅酶A：胆固醇酰基转移酶 (ACAT) 抑制剂 (IC50=0.18 μM)。 ACAT 催化胆固醇和长链脂肪酰辅酶 A 形成胆固醇酯。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥680 | 有现货 |
|
| 10MG | ￥1126 | 有现货 |
|
| 25MG | ￥2252 | 有现货 |
|
| 50MG | ￥3686 | 有现货 |
|
| 100MG | ￥5443 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称YM-750
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述YM-750 是一种有效的酰基辅酶A：胆固醇酰基转移酶 (ACAT) 抑制剂 (IC50=0.18 μM)。 ACAT 催化胆固醇和长链脂肪酰辅酶 A 形成胆固醇酯。
-
产品描述YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
-
体外实验Foam cells accumulated esterified cholesterol (EC) for 24 h in the presence of acLDL without Cu2+, which is suppressed by KY-455 and YM-750.
-
体内实验——
-
同义词YM 750 | YM-750
-
通路Others
-
靶点Other Targets
-
受体——
-
研究领域——
-
适应症——
化学信息
-
CAS Number138046-43-2
-
分子量452.642
-
分子式C31H36N2O
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 100 mg/mL (220.93 mM)
-
SMILESCc1cc(C)c(NC(=O)N(Cc2ccc-3c(Cc4ccccc-34)c2)C2CCCCCC2)c(C)c1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.P J Chu, et al. Antagonistic effect of N-(3-Aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cerebellar neurons. Jpn J Pharmacol. 1995 Dec;69(4):311-5.
产品手册
关联产品
-
3-Phosphoglyceric ac...
3-Phosphoglyceric acid 是一种糖酵解和卡尔文循环中的代谢中间体。3-Phosphoglyceric acid 可参与肺泡巨噬细胞的表观遗传调控。
-
1-hydroxy-3,5-dimeth...
1-hydroxy-3,5-dimethoxyxanthone
-
Cajanin
Cajanin has potential hypolipidemic effects,possibly via up-regulating the ABCA1 protein expression,subsequently resulting in increased macrophage cholesterol efflux and RCT, it can significantly improve basal glucose uptake in HepG2 cells, its improving effect is concentration dependent, it exhibits effects stronger than that of rosiglitazone, which has been used as an antidiabetic drug.
