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VT107
CAS No. 2417718-63-7
VT107 ( —— )
产品货号. M34767 CAS No. 2417718-63-7
VT-107 与 VT104 类似，是一种有效的 pan-TEAD 自棕榈酰化抑制剂。VT-107 可以用于癌症的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1899 | 有现货 |
|
| 5MG | ￥2980 | 有现货 |
|
| 10MG | ￥4490 | 有现货 |
|
| 25MG | ￥7007 | 有现货 |
|
| 50MG | ￥9540 | 有现货 |
|
| 100MG | ￥12623 | 有现货 |
|
| 500MG | ￥25169 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称VT107
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述VT-107 与 VT104 类似，是一种有效的 pan-TEAD 自棕榈酰化抑制剂。VT-107 可以用于癌症的研究。
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产品描述VT-107, as an analogous to VT104, is an orally active and potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer.
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体外实验Western Blot Analysis Cell Line:HEK293T cells Concentration:3 μmol/L Incubation Time:20 hours Result:Inhibited palmitoylation of both endogenous TEAD1 and TEAD3 proteins and was the most potent at blocking the palmitoylation of endogenous TEAD4 protein.
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体内实验Animal Model:MouseDosage:10 mg/kg (Pharmacokinetic Analysis) Administration:P.o.Result:Enantiomer analogous to VT104.
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同义词——
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通路Others
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靶点Other Targets
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受体YAP
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研究领域——
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适应症——
化学信息
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CAS Number2417718-63-7
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分子量435.44
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分子式C25H20F3N3O
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 100 mg/mL (229.65 mM; 超声助溶 )
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SMILESC[C@H](NC(=O)c1ccc2c(cccc2c1)-c1ccc(cc1)C(F)(F)F)c1cccc(N)n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Tang TT, et al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021; 20(6):986-998.?
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