Toddalolactone

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Toddalolactone，Toddalia asiatica 的主要成分，抑制重组人纤溶酶原激活物抑制物-1 (PAI-1) 的活性， IC50 为 37.31 μM。

anti-inflammatory and analgesic.

Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1.

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Metabolic Enzyme/Protease

P450

Others

Others-Field

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483-90-9

308.33

C16H20O6

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (162.16 mM)

CC(C)(C(CC1=C(C=C2C(=C1OC)C=CC(=O)O2)OC)O)O

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(-20℃)

With Ice Pack

≥ 2 years