Thiazovivin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Thiazovivin (Tzv) 是一种新型 ROCK 抑制剂，IC50 为 0.5 μM，可促进单细胞解离后 hESC 的存活。

Thiazovivin (Tzv) is a novel ROCK inhibitor with IC50 of 0.5μM, promotes hESC survival after single-cell dissociation.

Thiazovivin (GMP) (0.5 ?μM, at 1 day) promotes rapid and efficient reprogramming of mouse tail tip and embryonic fibroblasts into iPSCs.Thiazovivin (GMP) enhances the efficiency in reprograming endometrial adult stromal cells to iPSCs.Thiazovivin (GMP) (2 μM) induces iPSCs and induced neural stem cells (iNSCs) from human urine cells (UCs).Thiazovivin (GMP) (2 μM, for the first 24 h) improves growth rate of hiPSCs.Thiazovivin (GMP) (0.5 μM) together with SB431542 and PD0325901 promotes iPSC reprogramming by regulating cell-cell interactions.

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Tzv

Cell Cycle/DNA Damage

ROCK

ROCK

Cancer

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1226056-71-8

311.36

C15H13N5OS

>98% (HPLC)

DMSO: 15 mg/mL (48.17 mM)

O=C(C1=CSC(NC2=NC=NC=C2)=N1)NCC3=CC=CC=C3

N-(phenylmethyl)-2-(4-pyrimidinylamino)-4-thiazolecarboxamide

(-20℃)

With Ice Pack

≥ 2 years