Thermolysin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Thermolysin (EC 3.4.24.27) (TML) 是由革兰氏阳性菌 Bacillus thermoproteolyticus 分泌的耐热的中性金属蛋白酶。Thermolysin 可催化含有疏水残基的肽键水解。最佳 pH：8 0，在 pH 5.0- 9 5 范围内稳定最佳温度：70 °C

Thermolysin (EC 3.4.24.27) (TML) is a thermostable neutral metalloproteinase enzyme secreted by the Gram-positive bacteria Bacillus thermoproteolyticus. Thermolysin catalyzes the hydrolysis of peptide bonds containing hydrophobic residues.Optimal pH: 8.0. Considerably stable from pH 5 to 9.5.Optimal temperature : 70 °C

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Animal Model:Spontaneously hypertensive rats (SHR) rats Dosage:50 mg/kg Administration:Oral administration (p.o.), once Result:Lowered systolic blood pressure in SHR rats, with maximal reduction by 22 mm in systolic blood pressure being observed 6 h after administration.

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Proteasome/Ubiquitin

Endogenous Metabolite

Endogenous Metabolite

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9073-78-3

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>98% (HPLC)

In Vitro:?H2O 中的溶解度 : 1.96 mg/mL

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(-20℃)

With Ice Pack

≥ 2 years