Thalidomide-NH-CH2-COOH

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Thalidomide-NH-CH2-COOH 是一种合成的 E3 连接酶配体-接头缀合物，含有基于 Thalidomide 的 cereblon 配体和接头。

Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine | 2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetic acid

Others

Other Targets

α7 nAChR

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927670-97-1

331.28

C15H13N3O6

>98% (HPLC)

In Vitro:?DMSO : 50 mg/mL (150.93 mM)

OC(CNc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O)=O

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(-20℃)

With Ice Pack

≥ 2 years