Tenatoprazole ( TU-199 | Tenatoprazole | Ulsacare | Protop )

产品货号. M17835 CAS No. 113712-98-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Tenatoprazole
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

替那拉唑是质子泵抑制剂 (PPI) 类的前药，可以抑制质子转运 (IC50: 3.2 μM)。
产品描述

Tenatoprazole, also known as TU-199, is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer. Tenatoprazole has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump inhibitors, and has a half-life about seven times longer than other PPIs.
体外实验

——
体内实验

——
同义词

TU-199 | Tenatoprazole | Ulsacare | Protop
通路

Others
靶点

Other Targets
受体

Proton pump
研究领域

Inflammation/Immunology
适应症

——

CAS Number

113712-98-4
分子量

346.4
分子式

C16H18N4O3S
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 50 mg/mL (144.34 mM)
SMILES

COc1ccc2[nH]c(nc2n1)S(=O)Cc1c(C)c(OC)c(C)cn1
化学全称

5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-imidazo[4,5-b]pyridine

1. Shin JM, et al. Biochem Pharmacol, 2006, 71(6), 837-849.

计算器

产品手册

关联产品

[D-Arg1,D-Pro2,D-Trp...

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P 是神经肽 Substance P 的拮抗剂。
Pseudoginsenoside RT...

Pseudoginsenoside RT1 是从 Randia siamensis 的果实中分离出来的，具有急性鱼类毒性活性。
(D-Thr6,D-Trp8·9,L-a...

(D-Thr6,D-Trp8·9,L-alaninol15)-Galanin (1-15)