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TLR1
CAS No. 566914-00-9
TLR1 ( —— )
产品货号. M24556 CAS No. 566914-00-9
TLR1 是一种细胞穿透性 Toll/IL-1 受体/抗性 (TIR) 结构域/BB-Loop 模拟物，可抑制 IL-1 受体介导的反应。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2406 | 有现货 |
|
| 10MG | ￥3669 | 有现货 |
|
| 25MG | ￥5937 | 有现货 |
|
| 50MG | ￥7995 | 有现货 |
|
| 100MG | ￥11016 | 有现货 |
|
| 500MG | ￥22032 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称TLR1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述TLR1 是一种细胞穿透性 Toll/IL-1 受体/抗性 (TIR) 结构域/BB-Loop 模拟物，可抑制 IL-1 受体介导的反应。
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产品描述TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.
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体外实验TLR1 inhibits IL-1β-induced phosphorylation of the mitogen-activated protein kinase p38 in EL4 thymoma cells and in freshly isolated murine lymphocytes in a concentration-dependent manner.
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体内实验TLR1 interferes with the interactions between mouse MyD88 and IL-1RI at the TIR domains. TLR1 produces a significant attenuation of the IL-1β-induced fever response (200 mg/kg, i.p.).
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number566914-00-9
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分子量302.41
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分子式C18H26N2O2
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纯度>98% (HPLC)
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溶解度DMSO:10 mM
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SMILESCC(C)[C@@H](C(=O)N1CCCC1)NC(=O)CCC2=CC=CC=C2
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bartfai T, et al. A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7971-6.
产品手册
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