TH-Z93

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

TH-Z93，一种亲脂性双膦酸盐，是一种 FPPS 抑制剂 (IC50: 90 nM)。

TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM).

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TH-Z93 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model.Animal Model:B16-OVA cells (s.c.) xenograft mice model.Dosage:20 μg Administration:Intraperitoneal injection (i.p.)Result:Inhibited tumor growth and prolonged survival.

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GPCR/G Protein

Antibacterial

Antibacterial

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2260887-09-8

368.26

C12H22N2O7P2

>98% (HPLC)

In Vitro:?H2O 中的溶解度 : 1.89 mg/mL (5.13 mM; ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C)

C(NC1=CC(OCCCCCC)=CC=N1)(P(=O)(O)O)P(=O)(O)O

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(-20℃)

With Ice Pack

≥ 2 years