TH-Z145

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

TH-Z145，一种亲脂性双膦酸盐，是一种 FPPS 抑制剂 (IC50: 210 nM)。

TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).

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TH-Z145 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model.Animal Model:B16-OVA cells (s.c.) xenograft mice model.Dosage:20 μg Administration:Intraperitoneal injection (i.p.)Result:Inhibited tumor growth and prolonged survival.

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Others

Other Targets

Others

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2260887-57-6

394.34

C16H28O7P2

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (253.59 mM; 超声助溶 )

C(C(P(=O)(O)O)P(=O)(O)O)C1=CC(OCCCCCCCC)=CC=C1

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(-20℃)

With Ice Pack

≥ 2 years