Sulfuretin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Sulfuretin 是一种有效的抗氧化剂，对人肝源性 HepG2 细胞中 t-BHP 诱导的氧化损伤具有保护作用，这归因于其清除 ROS 并通过 Nrf2/ARE 上调 HO-1 活性的能力， JNK/ERK 信号通路。

Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.

Sulfuretin is one of the main flavonoids produced by Rhus verniciflua. Sulfuretin efficiently inhibits the infiltration of inflammatory cells and attenuates allergic airway inflammation.

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation. Animal Model:Pathogen-free male BALB/c mice (7-8 weeks old)Dosage:40 μg/kg Administration:A single intraperitoneal injection was administered 2 h after the last OVA challengeResult:Suppressed OVA-induced chemotaxis and airway inflammation.

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Autophagy

Autophagy

(HO)-1

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120-05-8

270.24

C15H10O5

>98% (HPLC)

DMSO:10 mM

C1=CC(=C(C=C1/C=C\2/C(=O)C3=C(O2)C=C(C=C3)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years