Sinapine ( —— )

产品货号. M18158 CAS No. 18696-26-9

COA

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产品名称

Sinapine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

芥子碱是一种来自十字花科植物种子的生物碱，可用作有效的天然化合物来抵抗化疗。
产品描述

Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. Sinapine has antioxidant and radio-protective activities.
体外实验

Sinapine (6 or 60 μM; 1 h) counteracts H2O2 and antimycin A-induced mitochondrial oxidative stress in cardiomyocytes.Sinapine (10-200 μM; 24 h) inhibits the proliferation of Caco-2 cells in a dose-dependent manner, and has relatively low toxicity.Sinapine (10-200 μM; 24 h) promotes doxorubicin accumulation in Caco-2 cell by inducing P-glycoprotein (P-gp) decrease.Sinapine (10-200 μM; 24 h) significantly reduces phosphorylation of FRS2α, ERK1/2.
体内实验

Sinapine reduces non-alcoholic fatty liver disease in mice by modulating the composition of the gut microbiota.
同义词

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Other Targets
受体

Antioxidant
研究领域

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适应症

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