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SM-6586
CAS No. 103898-38-0
SM-6586 ( —— )
产品货号. M33501 CAS No. 103898-38-0
SM-6586 是一种 calcium channel 的拮抗剂，同时能够抑制 Na+/H+ 和 Na+/Ca2+ exchange transport，主要用于研究脑血管疾病和高血压等疾病。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥9044 | 有现货 |
|
| 5MG | ￥14535 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称SM-6586
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SM-6586 是一种 calcium channel 的拮抗剂，同时能够抑制 Na+/H+ 和 Na+/Ca2+ exchange transport，主要用于研究脑血管疾病和高血压等疾病。
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产品描述SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension.
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体外实验——
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体内实验In SM-6586-treated spontaneously hypertensive rats, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher and lactate level. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. The brain water content is significantly decreased in the SM-treated group.
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同义词——
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体Sodium Channel | Na+/Ca2+ Exchanger
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研究领域——
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适应症——
化学信息
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CAS Number103898-38-0
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分子量489.52
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分子式C26H27N5O5
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(C1=C(C)NC(C)=C(C1C2=CC([N+]([O-])=O)=CC=C2)C3=NC(CN(CC4=CC=CC=C4)C)=NO3)OC
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Kashiwagi F, et al. Effect of a new calcium antagonist (SM-6586) on experimental cerebral ischemia. Acta Neurochir Suppl (Wien). 1994;60:289-92.?
