Rutin ( Rutoside | Rutin | Birutan | Eldrin | Oxyritin | Paliuroside | Sophorin | Venoruton | Yunxianggan )

产品货号. M12152 CAS No. 153-18-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Rutin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Rutin (Rutoside) 是一种广泛存在于多种植物中的黄酮类化合物，具有抗炎、降糖、抗氧化、神经保护、肾脏保护、肝脏保护和降低Aβ低聚物活性等多种生物活性。Rutin 能穿过血脑屏障。Rutin 通过抑制细胞凋亡、线粒体功能紊乱和氧化应激抑制万古霉素诱导的肾小管细胞凋亡。
产品描述

Rutin, a flavonol glycoside found in many plants including buckwheat; tobacco; forsythia; hydrangea; viola, etc., which possesses healthy effects for human.(In Vivo):Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signaling.
体外实验

——
体内实验

Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signaling.
同义词

Rutoside | Rutin | Birutan | Eldrin | Oxyritin | Paliuroside | Sophorin | Venoruton | Yunxianggan
通路

GPCR/G Protein
靶点

Prostaglandin Receptor
受体

AKR
研究领域

Inflammation/Immunology
适应症

——

CAS Number

153-18-4
分子量

610.52
分子式

C27H30O16
纯度

>98% (HPLC)
溶解度

Ethanol: 2 mg/mL (3.27 mM); DMSO: 122 mg/mL (199.82 mM)
SMILES

O=C1C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]3[C@@H]([C@@H]([C@H]([C@H](C)O3)O)O)O)O2)O)O)O)=C(C4=CC=C(O)C(O)=C4)OC5=CC(O)=CC(O)=C15
化学全称

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

1.Navarro-Nunez L, et al. J Agric Food Chem, 2008, 56(9), 2970-2976.

计算器

产品手册

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