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Ralfinamide
CAS No. 133865-88-0
Ralfinamide ( FCE-26742A | Priralfinamide )
产品货号. M20711 CAS No. 133865-88-0
Ralfinamide 是一种口服钠通道阻滞剂，用于治疗神经性疼痛和其他疼痛病症。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥365 | 有现货 |
|
| 10MG | ￥583 | 有现货 |
|
| 25MG | ￥1199 | 有现货 |
|
| 50MG | ￥2228 | 有现货 |
|
| 100MG | ￥3394 | 有现货 |
|
| 200MG | ￥5014 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ralfinamide
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Ralfinamide 是一种口服钠通道阻滞剂，用于治疗神经性疼痛和其他疼痛病症。
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产品描述Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.(In Vivo):Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain.
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体外实验——
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体内实验Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g)Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42Result:Suppressed neuropathic pain.
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同义词FCE-26742A | Priralfinamide
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通路Membrane Transporter/Ion Channel
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靶点Sodium Channel
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受体Na-channel
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研究领域Neurological Disease
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适应症Neuropathic pain
化学信息
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CAS Number133865-88-0
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分子量302.34
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分子式C17H19FN2O2
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纯度>98% (HPLC)
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溶解度DMSO:125 mg/mL (413.44 mM)
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SMILESC[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
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化学全称(2S)-2-(4-(2-Fluorobenzyloxy)benzylamino)propanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.
