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RSS0680
CAS No. 2769753-48-0
RSS0680 ( —— )
产品货号. M36605 CAS No. 2769753-48-0
RSS0680 (Example 22) 是一种靶向蛋白降解激酶的双功能化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥5155 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称RSS0680
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述RSS0680 (Example 22) 是一种靶向蛋白降解激酶的双功能化合物。
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产品描述RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体PROTACs | AMPK | CDK | AAK1 (AP2 associated kinase 1)
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研究领域——
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适应症——
化学信息
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CAS Number2769753-48-0
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分子量1021.32
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分子式C52H64N10O6S3
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 200 mg/mL (195.83 mM; 超声助溶 (<60°C)
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SMILESN(C=1N=C2C(=CSC2=CN1)C3=CC(NS(C)(=O)=O)=CC=C3)C4=CC=C(C=C4)N5CCN(CCCCCC(N[C@H](C(=O)N6[C@H](C(N[C@@H](C)C7=CC=C(C=C7)C8=C(C)N=CS8)=O)C[C@@H](O)C6)[C@@](C)(C)C)=O)CC5
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Gray Nathanael S, et al. Bifunctional compounds for targeted protein degradation of kinases: World Intellectual Property Organization, WO2022093742[P]. 2022-05-05.
产品手册
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