Perillartine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Perillartine 是一种甜味剂，激活味觉受体 1 型成员 2 (TAS1R2)。

Peryllartine is a sweetener that is about 2000 times as sweet as sucrose. Perillartine is the oxime of perillaldehyde.

The responses of the monomeric Tas1r2 subunits of human, rhesus monkey, squirrel monkey and mouse to Perillartine are examined, respectively. The human, rhesus monkey and squirrel monkey Tas1r2 subunits can be activated by Perillartine, while mouse Tas1r2 can not. The insensitivity of human, rhesus monkey, squirrel monkey and mouse Tas1r2 subunits to cyclamate precludes the probable involvement of Tas1r3 subunit in the assay. Replacement of the mouse Tas1r2 with rhesus monkey Tas1r2 (rhTas1r2/mTas1r3) leads to a gain of response to Perillartine. The dose-response curve show the efficacy of responses of the Tas1r2 subunits among species: hTAS1R2>rhTas1r2>smTas1r2>mTas1r2. These results demonstrate that the monomeric Tas1r2 subunit can be activated by Perillartine in a species-dependent manner.

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Peryllartine | AI3-52127 | Perilla sugar, Perillartine

Others

Other Targets

Others

Others-Field

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30950-27-7

165.23

C10H15NO

>98% (HPLC)

DMSO : ≥ 100 mg/mL 605.22 mM; H2O : < 0.1 mg/mL

CC(=C)C1CCC(=CC1)C=NO

(E)-4-(1-Methylvinyl)cyclohexene-1-carbaldehyde oxime

(-20℃)

With Ice Pack

≥ 2 years