PLGA

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PLGA 用于制造药物输送和组织工程应用的装置。

PLGA is be used to fabricate devices for drug delivery and tissue engineering applications.

Cell Viability Assay Cell Line:Calu-3 cellsConcentration:0.03-5 mg/mL (for PLgA (75:25)/PVA and PLgA (75:25)/CS); 3-5 mg/mL (for PLgA (75:25)/CS and PLgA (75:25)/PF68); 0.03-1 mg/mL (for PLgA (75:25)/PVA and PLgA (75:25)/PF68) (CS (chitosan), PF68 and PVA (poly vinyl alcohol) serve as cationic stabilizer)Incubation Time:72 h Result:Showed low toxicity to cells (cell viability was always higher than 50%) even at the highest concentration tested, when xposured to PLgA (75:25)/PVA, PLgA (75:25)/CS and PLgA (75:25)/PF68 nanoparticles.Increased cell viability, after short exposure (4 hours) to PLGA/PF68 nanoparticles.

Animal Model:Male Sprague-Dawley rats.Dosage:40 mg/kg (dose of Risperidone, PLGA (75:25) as a drug delivery carrier).Administration:Subcutaneous injection; single.Result:Achieved slow release in vivo: after an initial burst, a sharp drop occurred and the drug levels through day 22 remained in a steady manner while progressing to a decline up to day 45.

poly(lactic-co-glycolic acid)

Others

Other Targets

GABAA

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34346-01-5

166.13

C5H10O6

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL

O=C(O)C(C)OC(CO[H])=O.[x].[y]

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(-20℃)

With Ice Pack

≥ 2 years