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O-Phosphorylethanolamine

CAS No. 1071-23-4

O-Phosphorylethanolamine ( —— )

产品货号. M19543 CAS No. 1071-23-4

磷酸乙醇胺 (PE) 是磷脂代谢的磷酸单酯代谢物。 PE是磷脂合成的前体,也是磷脂分解的产物。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥235 有现货

生物学信息

  • 产品名称
    O-Phosphorylethanolamine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    磷酸乙醇胺 (PE) 是磷脂代谢的磷酸单酯代谢物。 PE是磷脂合成的前体,也是磷脂分解的产物。
  • 产品描述
    Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown. Phosphomonoesters are present at much higher levels in the brain than in other organs. In developing the brain phosphomonoesters are normally elevated during the period of neuritic proliferation. This also coincides with the occurrence of normal programmed cell death and synaptic pruning in developing the brain. These findings are consistent with the role of phosphomonoesters in membrane biosynthesis. PE shows a strong structural similarity to the inhibitory neurotransmitter GABA and the GABAB receptor partial agonist 3-amino-propylphosphonic acid. PE is a phosphomonoester which is decreased in post-mortem Alzheimer's disease (AD) brain.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1071-23-4
  • 分子量
    141.06
  • 分子式
    C2H8NO4P
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O:250 mg/mL (1772.30 mM; Need ultrasonic)
  • SMILES
    NCCOP(O)(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Klunk W E et al. Inactivity of phosphoethanolamine an endogenous GABA analog decreased in Alzheimer's disease at GABA binding sites[J]. Life Sciences 1995 56(26):2377.
产品手册
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