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Neurotensin(8-13)
CAS No. 60482-95-3
Neurotensin(8-13) ( —— )
产品货号. M30135 CAS No. 60482-95-3
Neurotensin (8-13) is a neuropeptide that corresponds to the C-terminal residues 8-13 of neurotensin that binds to rat synaptic membranes with a Ki value of 13 nM.1 It induces contraction of guinea pig ileum (EC50 = 25 nM) and induces contraction of rat fundus equipotently to full length neurotensin (EC50s = 1.29 and 1.58 nM, respectively).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥425 | 有现货 |
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| 5MG | ￥540 | 有现货 |
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| 10MG | ￥936 | 有现货 |
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| 25MG | ￥2059 | 有现货 |
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| 50MG | ￥2671 | 有现货 |
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| 100MG | ￥3470 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
生物学信息
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产品名称Neurotensin(8-13)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Neurotensin (8-13) is a neuropeptide that corresponds to the C-terminal residues 8-13 of neurotensin that binds to rat synaptic membranes with a Ki value of 13 nM.1 It induces contraction of guinea pig ileum (EC50 = 25 nM) and induces contraction of rat fundus equipotently to full length neurotensin (EC50s = 1.29 and 1.58 nM, respectively).
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产品描述Neurotensin (8-13) is a neuropeptide that corresponds to the C-terminal residues 8-13 of neurotensin that binds to rat synaptic membranes with a Ki value of 13 nM.1 It induces contraction of guinea pig ileum (EC50 = 25 nM) and induces contraction of rat fundus equipotently to full length neurotensin (EC50s = 1.29 and 1.58 nM, respectively).(In Vitro):Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.
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体外实验——
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体内实验——
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同义词——
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通路GPCR/G Protein
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靶点Neurotensin Receptor
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受体NTR1
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研究领域——
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适应症——
化学信息
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CAS Number60482-95-3
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分子量816.99
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分子式C38H64N12O8
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纯度>98% (HPLC)
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溶解度H2O : 50 mg/mL (61.20 mM; Need ultrasonic)
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SMILES——
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化学全称Sequence:Arg-Arg-Pro-Tyr-Ile-Leu
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
García-Garayoa E, et al. Preclinical evaluation of a new, stabilized neurotensin(8--13) pseudopeptide radiolabeled with (99m)tc. J Nucl Med. 2002 Mar;43(3):374-83.
产品手册
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