Necroptosis-IN-3 ( —— )

产品货号. M35795 CAS No. 547698-18-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Necroptosis-IN-3
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Necroptosis-IN-3 (Compound 69) 是一种坏死性凋亡 (necroptosis) 抑制剂，抑制 TNF-α 诱导的坏死性凋亡。Necroptosis-IN-3 (Compound STX1638) 也抑制 11β-HSD1。
产品描述

Necroptosis-IN-3 (Compound 69) is a necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.
体外实验

Cell Viability Assay Cell Line:Fadd-/- Jurkat and L929 cells, treated with 10 ng/mL of human TNF-α Concentration:0.030-100 μM Incubation Time:24 h Result:Showed necroptosis inhibitory activity with an ED50 of 7.724 μM for Fadd-/- Jurkat cells and was inactive for L929 cells.
体内实验

——
同义词

——
通路

Others
靶点

Other Targets
受体

Necroptosis
研究领域

——
适应症

——

1. Junying Yuan, et al. Small molecule inhibitors of necroptosis. Patent US20120122889A1.

计算器

产品手册

关联产品

Dehydrodiconiferyl a...

Dehydrodiconiferyl alcohol (DHCA) is a lignan isolated from calabash that inhibits osteoclast differentiation and oophorectomy induced bone loss by acting as an estrogen receptor agonist.
Ascomycin

Ascomycin(Immunomycin, FR-900520, FK520) 是他克莫司 (FK506) 的乙基类似物，具有很强的免疫抑制特性。
Palladium (II) aceta...

Palladium (II) acetate is a catalyst that catalyzes aromatic substitution reactions.