NP-G2-044

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

NP-G2-044 是一种口服活性肌成束蛋白抑制剂，IC50 约为 2 μM。它可以阻止肿瘤转移并增加抗肿瘤免疫反应。

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

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Animal Model:6-8 week old female BALB/c mice (mouse model bearing 4T1 tumor cells) Dosage:100 mg/kg Administration:I.p.; daily for 18 days Result:Inhibition of 4T1 mouse mammary tumor cell metastasis to the lung.

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Others

Other Targets

fascin

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1807454-59-6

399.37

C21H16F3N3O2

>98% (HPLC)

DMSO:100 mg/mL (250.39 mM; Need ultrasonic)

Cc(occ1)c1C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2c1cccc2)=O

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(-20℃)

With Ice Pack

≥ 2 years