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Mito-TEMPO
CAS No. 1334850-99-5
Mito-TEMPO ( —— )
产品货号. M23487 CAS No. 1334850-99-5
Mito-TEMPO 是一种靶向线粒体的超氧化物歧化酶模拟物。 Mito-TEMPO 具有超氧化物和烷基自由基清除特性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥413 | 有现货 |
|
| 10MG | ￥721 | 有现货 |
|
| 25MG | ￥1442 | 有现货 |
|
| 50MG | ￥2778 | 有现货 |
|
| 100MG | ￥4625 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Mito-TEMPO
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Mito-TEMPO 是一种靶向线粒体的超氧化物歧化酶模拟物。 Mito-TEMPO 具有超氧化物和烷基自由基清除特性。
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产品描述Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO with superoxide and alkyl radical scavenging properties.(In Vivo):Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.
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体外实验——
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体内实验Mito-TEMPO (MT) greatly attenuates the increase in ALT activities and reduces the areas of necrosis at both time points, indicating that the protection by Mito-TEMPO is sustained until at least 24 h post-APAP. Mito-Tempo could induce secondary apoptosis in the late phase of APAP hepatotoxicity. Mito-Tempo induces secondary apoptosis after APAP overdose by inhibition of RIP3.
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同义词——
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通路Others
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靶点Other Targets
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受体Mitochondrial Metabolism
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研究领域——
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适应症——
化学信息
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CAS Number1334850-99-5
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分子量510.03
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分子式C29H35ClN2O2P
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纯度>98% (HPLC)
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溶解度DMSO:125 mg/mL (245.08 mM; Need ultrasonic);H2O:60 mg/mL (117.64 mM; Need ultrasonic)
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SMILES[O]N1C(C)(C)CC(NC(C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)=O)CC1(C)C.[Cl-]
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Du K, et al. Mito-tempo protects against acute liver injury but induces limited secondary apoptosis during the late phase of acetaminophen hepatotoxicity. Arch Toxicol. 2018 Oct 15.
产品手册
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