Mepacrine ( —— )

产品货号. M34002 CAS No. 83-89-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Mepacrine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Quinacrine (Acriquine) 是一种抗疟疾和抗癌剂。Quinacrine 还抑制人醛氧化酶 (aldehyde oxidase) (IC50: 3.3 μM)。Quinacrine 对核酸具有亲和力，并对固定细胞中的 DNA 和 RNA 染色 (Ex/Em: 436/525 nm)。
产品描述

Quinacrine (Acriquine) is an antimalarial and anti-cancer agent. Quinacrine also inhibits human aldehyde oxidase (IC50: 3.3 μM). Quinacrine has affinity for nucleic acids, and stains DNA and RNA in fixed cells (Ex/Em: 436/525 nm).
体外实验

Cell Viability Assay Cell Line:SGC-7901 cell Concentration:0, 5, 10, 15, 20 μM Incubation Time:24 h Result:Inhibited cell growth with an IC50 value of 16.18 μM.
体内实验

Animal Model:Acute kidney injury rat model Dosage:3-30 mg/kg Administration:i.p.Result:Attenuated glycerol induced structural and functional changes in kidney.
同义词

——
通路

Others
靶点

Other Targets
受体

Others
研究领域

——
适应症

——

1. Vogtherr M, et al. Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein. J Med Chem. 2003 Aug 14;46(17):3563-4. ?

计算器

产品手册

关联产品

20(R)-Notoginsenosid...

20(R)-Notoginsenoside R2 is a natural product with Promote blood circulation and improve myocardial ischemia.
Vanillic Acid

香草酸在食品中用作调味品，用于酒、醋中。它是从阿魏酸生产香草醛的中间体。
N-phenylacetyl-L-Hom...

N-phenylacetyl-L-Homoserine lactone attenuates the group sensing of the pathogen Acinetobacter baumannii and can be used to study bacterial infections.