MCT1-IN-3

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

MCT1-IN-3 是一种单羧酸转运蛋白 1 (MCT1) 抑制剂，IC50 值为 81.0 nM。MCT1-IN-3 还对多药转运蛋白 ABCB1 具有显著的抑制作用。MCT1-IN-3 可用于癌症的研究。

MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1)inhibitor with an IC50 value of 81.0 nM. MCT1-IN-3 has also significant inhibitivity against the multidrug transporter ABCB1. MCT1-IN-3 can be used for the research of cancer.

Cell Cycle AnalysisCell Line:A-549 cells Concentration:5 μM Incubation Time:24 h Result:Caused a disruption of the cell cycle of A-549 cancer cells, indicated by a shift from the predominant Go/G, phase.Apoptosis Analysis Cell Line:A-549 cells Concentration:5 μM Incubation Time:24 h Result:Increased the percentage of total apoptotic cells by a factor of 13 from 0.51 to 6.68%.

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Membrane Transporter/Ion Channel

Monocarboxylate Transporter

Monocarboxylate transporter

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2878360-80-4

389.4

C22H19N3O4

>98% (HPLC)

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C(=C(C(OC)=O)C#N)C=1C=2C(N(CC(NC3=CC=C(OC)C=C3)=O)C1)=CC=CC2

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(-20℃)

With Ice Pack

≥ 2 years