Ganoderic acid beta is a constituent from the fruiting body of Ganoderma lucidum (Fr.) Karst.

Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM); first isolated from bovine adrenal medulla. Unlike BAM 22P , does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors.

KRAS G12C inhibitor 16 是一种有效的 KRAS G12C 抑制剂，IC50 为 97 nM，详细信息请参考专利文献 WO2019110751A1 中的化合物 39。