Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.

14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.

Dihydrobetulinic acid is a bioactive chemical.