Ac-IETD-pNA
CAS No. 219138-21-3
Ac-IETD-pNA ( ——— )
产品货号. M41648 CAS No. 219138-21-3
Ac-Ile-Glu-Thr-Asp-pNA是 caspase-8 的底物。Caspase-8 结合并裂解Ile-Glu-Thr-Asp (IETD) 肽序列,释放对硝基苯胺,可通过 405 nm 处的比色检测来定量检测酶活性。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥1121 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Ac-IETD-pNA
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ac-Ile-Glu-Thr-Asp-pNA是 caspase-8 的底物。Caspase-8 结合并裂解Ile-Glu-Thr-Asp (IETD) 肽序列,释放对硝基苯胺,可通过 405 nm 处的比色检测来定量检测酶活性。
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产品描述Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8.Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
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体外实验———
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体内实验———
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同义词———
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通路Others
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靶点Other Targets
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受体———
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研究领域———
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适应症———
化学信息
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CAS Number219138-21-3
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分子量638.6
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分子式C27H38N6O12
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纯度>98% (HPLC)
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溶解度H2O : 0.98 mg/mL (1.53 mM; adjust pH to 12 with 1 M NaOH)
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Smith GK, et al. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Arch Biochem Biophys. 2002;399(2):195-205.?
产品手册
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