[D-Ala4]-Substance P (4-11) ( ——— )

产品货号. M41639 CAS No. 81381-50-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

[D-Ala4]-Substance P (4-11)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

[DAla4] Substance P (4-11) 是 Substance P (Substance P ) 的类似物，可抑制 125I-Bolton Hunter 偶联的 Eledoisin (IC50 为 0.5 μM) 和 125I-Bolton Hunter 偶联的 Substance P (IC50 为 0.15 μM) 与大鼠大脑皮层膜的结合。
产品描述

[DAla4] Substance P (4-11) is an analog of Substance P (Substance P ) that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes.
体外实验

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体内实验

Eledoisin 和 Substance P 是速激肽的一类肽成员，它们具有相似的生物活性谱。[DAla4] Substance P (4-11) ([D-Ala0-(5-11)]SP) 抑制 125I-Bolton Hunter-conjugated 偶联的 Eledoisin 和 125I-Bolton Hunter 偶联的 Substance P 与大鼠大脑皮层膜的结合。
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1. M A Cascieri, et al. Demonstration of two distinct tachykinin receptors in rat brain cortex. J Biol Chem. 1985 Feb 10;260(3):1501-7.?

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