α-ANF(1-28), human

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Atrial natriuretic factor (1-28) (human, porcine) 是 pro-opiomelanocortin (POMC) mRNA 的强效抑制因子和βEP-LI释放的弱抑制因子。

Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM.

ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study.

ANF-(1-28) markedly increaseS guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10(6) cells [50% effective dosage (ED50) = 1.2 nM].

———

Others

Other Targets

———

———

———

91917-63-4

3080.46

C127H203N45O39S3

>98% (HPLC)

———

———

———

(-20℃)

With Ice Pack

≥ 2 years