Osteocalcin (45-49) (human) ( ——— )

产品货号. M40062 CAS No. 85679-70-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Osteocalcin (45-49) (human)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Bone Gla Protein (45-49) 是来自骨 (BGP, 骨钙素) 的含有羧基谷氨酸 (Gla) 的蛋白质片段 (45-49)，Bone Gla Protein对在体外对体内靠近骨内膜表面的许多细胞具有趋化活性。
产品描述

Bone Gla Protein (45-49) is the 45-49 fragment of gamma-carboxyglutamic acid (GLA)-containing protein from bone (BGP, osteocalcin), which has chemotactic activity in vitro for a number of cells which are found adjacent to endosteal bone surfaces in vivo.
体外实验

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体内实验

Bovine bone Gla protein (BGP) (1 nM-10 μM) exerts chemotactic activity of (0.1 and 1 μM) cultured human breast cancer cells (MDA-MB-231 cells), (1 nM-1 μM) human peripheral blood monocytes, and (1-10 μM) rat osteosarcoma cells with osteoblast-like characteristics.
同义词

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通路

Others
靶点

Other Targets
受体

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研究领域

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适应症

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1. Mundy GR, et al. Chemotactic activity of the gamma-carboxyglutamic acid containing protein in bone. Calcif Tissue Int. 1983;35(2):164-8. ?

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