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(Tyr0,Trp2)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor
(Tyr0,Trp2)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor
CAS No. 144450-13-5
(Tyr0,Trp2)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor ( ——— )
产品货号. M40022 CAS No. 144450-13-5
Tyr-W-MIF-1 是一种阿片四肽，具有阿片和抗阿片活性。Tyr-W-MIF-1 可诱导镇痛。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | 获取报价 | 有现货 |
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| 50MG | 获取报价 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
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| 1G | 获取报价 | 有现货 |
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生物学信息
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产品名称(Tyr0,Trp2)-Melanocyte-Stimulating Hormone-Release Inhibiting Factor
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Tyr-W-MIF-1 是一种阿片四肽，具有阿片和抗阿片活性。Tyr-W-MIF-1 可诱导镇痛。
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产品描述Tyr-W-MIF-1 is an opioid tetrapeptide with opiate and antiopiate activity. Tyr-W-MIF-1 can induce analgesia.
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体外实验Tyr-W-MIF-1 (i.c.v，5 μL, 200 μg) 诱导大鼠镇痛时间延长。Tyr-W-MIF-1 (i.t., 0.75 μg) 诱导镇痛，并被 Naloxone 逆转。Animal Model:Rats Dosage:200 μg in 5 μL Administration:Intracerebroventricular injection (i.c.v)Result:Prolonged analgesia, measured by latency to remove the tail from a heating element.
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体内实验Tyr-W-MIF-1 (1-10 μM) 抑制 LC 神经元的自发放电。Tyr-W-MIF-1 减弱 Morphine (3 μM) 诱导的 SH-SY5Y 人神经母细胞瘤细胞中 mu 和 delta 受体的下调。Tyr-W-MIF-1 (0.3 μM) 抑制3H-DAMGO (对μ阿片受体有选择性) 与大鼠脑的结合。
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同义词———
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通路Others
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靶点Other Targets
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受体———
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研究领域———
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适应症———
化学信息
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CAS Number144450-13-5
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分子量520.59
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分子式C27H32N6O5
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纯度>98% (HPLC)
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溶解度———
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Yang YR, et L. Opioid and antiopioid actions of Tyr-MIF-1, Tyr-W-MIF-1 and hemorphin-4 on rat locus coeruleus neurons: intracellular recording in vitro. Chin J Physiol. 1997 Sep 30;40(3):131-5. ?
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