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Apelin-12 (human, bovine, mouse, rat)
CAS No. 229961-08-4
Apelin-12 (human, bovine, mouse, rat) ( ——— )
产品货号. M39852 CAS No. 229961-08-4
Apelin-12 是多肽中最有效的 C 端片段之一，对孤儿受体 APJ 受体具有很高的亲和力。Apelin-12 参与体液平衡的调节和摄食的中枢控制。Apelin-12 阻断HIV-1通过 APJ 受体进入。Apelin-12 具有神经保护作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 25MG | ￥7431 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Apelin-12 (human, bovine, mouse, rat)
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Apelin-12 是多肽中最有效的 C 端片段之一，对孤儿受体 APJ 受体具有很高的亲和力。Apelin-12 参与体液平衡的调节和摄食的中枢控制。Apelin-12 阻断HIV-1通过 APJ 受体进入。Apelin-12 具有神经保护作用。
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产品描述Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect.
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体外实验———
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体内实验Apelin-12 (A12) exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and p38 MAPK signaling pathway in mouse.Administration of exogenous A12 reduces arterial blood pressure in anesthetized rats due to activation of endothelial nitric oxide synthase and exerts a positive inotropic action in failing myocardium of rodents.Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs.
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同义词———
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通路Others
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靶点Other Targets
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受体HIV-1
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研究领域———
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适应症———
化学信息
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CAS Number229961-08-4
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分子量1422.72
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分子式C64H103N21O14S1
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纯度>98% (HPLC)
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溶解度?H2O : ≥ 100 mg/mL (70.29 mM)
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SMILES———
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化学全称———
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203.?
产品手册
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