(7S,8S)-Threo-7,9,9′-trihydroxy-3,3′-dimethoxy-8-O-4′-neolignan-4-O-β-D-glucopyranoside (compound 16) is a lignin glycoside that can be isolated from the fruits of Arctium lappa (burdock, Asteraceae).

New compound 12 (Rhoifolin analog)

TUG-424 在 100 nM 时可显着增强葡萄糖刺激的胰岛素分泌。 TUG-424 是一种有效的选择性游离脂肪酸受体 1 激动剂 (EC50: 32 nM)。