4,5-dehydroisopsoralidin ( 4",5"-去氢异补骨脂定 )

产品货号. M38999 CAS No. 65639-51-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

4,5-dehydroisopsoralidin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

4'',5''-Dehydroisopsoralidin 是一种 β-葡萄糖醛酸酶 (β-glucuronidase) 抑制剂(IC50: 6.3 μM)。4'',5''-Dehydroisopsoralidin 具有抗炎和抗氧化作用。4'',5''-Dehydroisopsoralidin 可用于炎症和癌症的研究。
产品描述

4'',5''-Dehydroisopsoralidin is a β-glucuronidase inhibitor (IC50: 6.3 μM). 4'',5''-Dehydroisopsoralidin has anti-inflammatory and anti-oxidative effects. 4'',5''-Dehydroisopsoralidin can be used in the research of inflammation and cancners.
体外实验

———
体内实验

4'',5''-Dehydroisopsoralidin (compound 5, 15 min) inhibits the release of β-glucuronidase in polymorphonuclear leukocytes (PMNs) of rats, with an IC50 value of 6.3 μM.4'',5''-Dehydroisopsoralidin (compound 9, 24 h) shows weak cytotoxicity (IC50: >50 μM) to H4IIE, HCT116, C6 cells.4'',5''-Dehydroisopsoralidin (25 μM, 1h) causes significant radical scavenging in H4IIE rat hepatoma cells (TEAC assay).4'',5''-Dehydroisopsoralidin (compound 5, 15 μM, 60 h) increases lifespan in P. corylifolia (MEP assay).
同义词

4",5"-去氢异补骨脂定
通路

Others
靶点

Other Targets
受体

———
研究领域

———
适应症

———

1. De-Wu Zhang, et al. Solalyratins A and B, new anti-inflammatory metabolites from Solanum lyratum. J Nat Med. 2012 Apr;66(2):362-6. ?

计算器

产品手册

关联产品

6-Epiagarotetrol

6-Epiagarotetrol 是一种可以从 Aquilaria sinensis 中提取得到的神经保护剂。6-Epiagarotetrol 对 corticosterone 诱导的PC12细胞损伤具有保护作用。
Styrene oxide

氧化苯乙烯是衍生自苯乙烯的环氧化物。可由苯乙烯与过苯甲酸环氧化而制得。
Cortistatin-29 (rat)

Cortistatin-29 is a neuropeptide. Cortistatin-29 alleviates neuropathic pain. Cortistatin-29 binds all somatostatin (SS) receptor subtypes with high affinity and shows IC50 values of 2.8 nM, 7.1 nM, 0.2 nM, 3.0 nM, 13.7 nM for SSTR1, SSTR2, SSTR3, SSTR4, SSTR5, respectively. Cortistatin-29 shows anti-fibrotic effects.