RO5166017 是具有口服活性的、跨物种的 TAAR1 的激动剂，其对小鼠、大鼠、人和食蟹猴的 Ki 值分别为1.9 nM、2.7 nM、31 nM 和 24 nM。

Orexin A human, rat, mouse, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A human, rat, mouse has been used to study its effect on the functioning of porcine pancreatic islets. It has also been used as an orexin receptor 1 (OX1R) antagonist to study the effect of orexin systems in the effect of etonogestrel on respiratory response to prolonged metabolic acidosis.

6-CFDA 是荧光聚阴离子探针，用于测量细胞内 pH (pHi) 的变化以及树枝状聚合物聚集和吸收等过程。