Ciwujianoside C3

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Ciwujianoside C3 是一种具有口服活性并可以穿透血脑屏障的化合物，分离于刺五加的叶子。 Ciwujianoside C3 具有抗炎作用，并可以增强小鼠个体的识别记忆力。

Ciwujianoside?C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax?henryi Harms. Ciwujianoside?C3 has anti-inflammatory effect and can reinforces object recognition memory.

Animal Model:Mice Dosage:0.5 mg/kg Administration:Oral administration; 0.5 mg/kg/day; 17 days Result:Reinforced object recognition memory.

Cell Viability Assay Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreases p-ERK and p-JNK expression. RT-PCR Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.

刺五加苷C3

Immunology/Inflammation

NOS

NO Synthase

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114906-74-0

1059.25

C53H86O21

>98% (HPLC)

DMSO : 50 mg/mL (47.20 mM; ultraphonic; )

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(-20℃)

With Ice Pack

≥ 2 years