Euparine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Euparin 是苯并呋喃的单体化合物，是一种活性氧 (ROS) 抑制剂。 Euparin 对脊髓灰质炎病毒具有抗病毒活性，并且还具有抗抑郁作用。

Euparin, a monomeric compound of Benzofuran, is a reactive oxygen species (ROS) inhibitor. Euparin shows antiviral activity against poliovirus, and also has antidepressant effects.

Euparin (8, 16 and 32 mg/kg) reduces depression-like behavior in Chronic Unpredictable Mild Stress (CUMS) model of mice. All doses of Euparin are found to increase the contents of monoamine neurotransmitter and decrease monoamine oxidase and reactive oxygen species (ROS) levels in brain of depression mice. Euparin restores CUMS-induced decrease of Spermidine/Spermine N1-Acetyltransferase 1 (SAT1), N-methyl-D-aspartate receptor subtype 2B (NMDAR2B) and brain derived neurotrophic factor (BDNF) expression.

In Vero cells, Euparin shows antiviral activity against poliovirus types 1, 2, and 3 with EC50 values of 0.47 μg/mL, 0.12 μg/mL, and 0.15 μg/mL, respectively.

泽兰素

Microbiology/Virology

Antifection

Antifection

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532-48-9

216.23

C13H12O3

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years