Methylene Violet 3RAX

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Methylene Violet 3RAX 是一种吩嗪染料，用于染色细胞的线粒体。Methylene Violet 3RAX 可以改变DNA的分子结构，破坏DNA的模块，诱导活性单线态氧的产生。Methylene Violet 3RAX 对人红细胞 AChE 和人血浆 BChE 具有抑制作用，Kis 分别为 1.58 和 0.51 μM。Methylene Violet 3RAX 具有研究PDT (光动力疗法) 中线粒体靶向作用的潜在光敏剂的潜力。

Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy).

Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell.Methylene Violet 3RAX (0-400 μM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM.

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Others

Other Targets

Others

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4569-86-2

378.9

C22H23ClN4

>98% (HPLC)

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N(CC)(CC)C1=CC=2[N+](=C3C(=NC2C=C1)C=CC(N)=C3)C4=CC=CC=C4.[Cl-]

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(-20℃)

With Ice Pack

≥ 2 years