Oxelumab

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Oxelumab (R 4930) 是一种靶向 OX40 配体 (OX40L) 的人单克隆抗体。Oxelumab 可用于哮喘的研究。

Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma.

Cell Proliferation Assay Cell Line:Natural Killer (NK) cell lines Concentration:10 μg/mL Incubation Time:3 days Result:Inhibited cell proliferation of NK cells.

Animal Model:NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI) Dosage:5 and 30 mg/kg Administration:Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13 Result:Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.

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Others

Other Targets

Interleukin

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1186098-83-8

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>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years