Fletikumab ( —— )

产品货号. M36697 CAS No. 1357158-22-5

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产品名称

Fletikumab
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Fletikumab (NNC0109-0012) 是一种靶向 IL-20 的单克隆抗体。Fletikumab 可用于炎症研究，如类风湿关节炎。
产品描述

Fletikumab (NNC0109-0012) is a monoclonal antibody targeting to IL-20. Fletikumab can be used for inflammation research, such as rheumatoid arthritis.
体外实验

Fletikumab blocks IL-20 binding IL-20 receptor, acts potential function of inflammation inhibition.IL-20 is a member of IL-10 family, which includes IL-10, IL-19, IL-22, IL-24, IL-26, IL-28, and IL-29. IL-20 acts on renal cells and contributes to inflammation, fibrosis, and apoptosis through its receptors IL-20R1, IL-20R2, and IL-22R1.
体内实验

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通路

Others
靶点

Other Targets
受体

Interleukin
研究领域

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适应症

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1. Kragstrup TW, et al. The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis. Front Immunol. 2018 Sep 25;9:2226.? ?

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