Ac-Pro-Gly-Pro-OH ( —— )

产品货号. M36655 CAS No. 292171-04-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ac-Pro-Gly-Pro-OH
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ac-Pro-Gly-Pro-OH 是细胞外胶原蛋白的内源性降解产物，可用作CXCR2 激动剂。Ac-Pro-Gly-Pro-OH 具有杀菌活性并抑制肺部炎症，减少免疫细胞凋亡。Ac-Pro-Gly-Pro-OH 增强 1 型细胞因子(IFN-γ 和 IL-12) 的产生，但抑制促炎细胞因子的产生。Ac-Pro-Gly-Pro-OH 具有用于脓毒症研究的潜力。
产品描述

Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis.
体外实验

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体内实验

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同义词

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通路

Apoptosis
靶点

Apoptosis
受体

Apoptosis | CXCR | Antibiotic
研究领域

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适应症

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1. Patel DF, et al The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease. Eur Respir Rev. 2018 Jun 27;27(148):180017.?

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