Navamepent

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Navamepent 是 resolvin E1 (一种主要的膳食-3多不饱和脂肪酸代谢物)的类似物，具有强大的抗炎和细胞生存益处。Navamepent对干眼和杯状细胞损失非常有效，从而加速泪液的产生。Navamepent还能减少角膜炎症、上皮损伤，加速角膜组织修复。此外，Navamepent可抑制角膜上皮细胞释放几种关键促炎介质。Navamepent 是一种点击化学试剂。它含有 Alkyne 基团，可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

Navamepent is an analog of naturally occurring resolvin E1 (a major dietary omega-3 polyunsaturated fatty-acid metabolite) with potent anti-inflammatory and cell survival benefits. Navamepent is highly effective against dry eye and goblet cell loss thereby accelerating tear production. Also, Navamepent can reduce corneal inflammation, epithelial damage, and accelerate corneal tissue repair. In addition, Navamepent can inhibit the release of several key proinflammatory mediators from corneal epithelial cells. Navamepent is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Others

Other Targets

Others

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1251537-11-7

304.38

C18H24O4

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 100 mg/mL (328.54 mM; 超声助溶 )

C(C[C@@H](C#C/C=C/C=C/[C@@H](CC#C)O)O)CC(OC(C)C)=O

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(-20℃)

With Ice Pack

≥ 2 years