dCeMM1 ( —— )

产品货号. M35978 CAS No. 118719-16-7

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

dCeMM1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

dCeMM1 是一种 RBM39 分子胶降解剂。dCeMM1 通过重定向 CRL4DCAF15 连接酶的活性发挥作用。dCeMM1 降低 WT KBM7 细胞中 RBM39 水平的表达。
产品描述

dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells.
体外实验

Western Blot Analysis Cell Line:WT and UBE2Mmut KBM7 cells Concentration:10 μM Incubation Time:12, 16 h Result:Decreased the expression of RBM39 levels in WT KBM7 cells.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Molecular Glues
研究领域

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适应症

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1. Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.

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