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Anti-inflammatory agent 36
CAS No. 2293951-01-4
Anti-inflammatory agent 36 ( —— )
产品货号. M35803 CAS No. 2293951-01-4
Anti-inflammatory agent 36 是一种抗炎剂。Anti-inflammatory agent 36 抑制 LPS 诱导的巨噬细胞活化。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥425 | 有现货 |
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| 10MG | ￥701 | 有现货 |
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| 25MG | ￥1330 | 有现货 |
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| 50MG | ￥2167 | 有现货 |
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| 100MG | ￥3060 | 有现货 |
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| 500MG | ￥6183 | 有现货 |
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| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥505 | 有现货 |
|
生物学信息
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产品名称Anti-inflammatory agent 36
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Anti-inflammatory agent 36 是一种抗炎剂。Anti-inflammatory agent 36 抑制 LPS 诱导的巨噬细胞活化。
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产品描述Anti-inflammatory agent 36 is an anti-inflammatory agent. Anti-inflammatory agent 36 inhibits LPS-induced macrophage activation.
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体外实验Western Blot Analysis Cell Line:RAW 264.7 mouse macrophages Concentration:10 μM Incubation Time:0.5 h Result:Markedly inhibited P-P38 and P-ERK, indicating the suppression of MAPK signaling.
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体内实验Animal Model:Acute lung injury mouse model Dosage:10 mg/kg Administration:i.p.Result:Reduced wet/dry weight ratio of the mice lungs.Reduced biomarkers of lymphocytes and macrophages.Suppresses TNF-α, IL-6, IL-1β, 7 VACM-1 and ICAM-1 level.
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同义词——
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通路Others
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靶点Other Targets
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受体Immunology/Inflammation related
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研究领域——
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适应症——
化学信息
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CAS Number2293951-01-4
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分子量453.48
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分子式C25H27NO7
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 25 mg/mL (55.13 mM; 超声助溶 (<60°C)
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SMILESCOc1cc(\C=C\C(=O)N2CCC\C(=C/c3cc(OC)c(OC)c(OC)c3)C2=O)ccc1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Qian J, et al. Design and synthesis novel di-carbonyl analogs of curcumin (DACs) act as potent anti-inflammatory agents against LPS-induced acute lung injury (ALI). Eur J Med Chem. 2019 Apr 1;167:414-425. ?
产品手册
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