AIMP2-DX2-IN-1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

AIMP2-DX2-IN-1 (Compound 35) 是一种有效的 AIMP2-DX2 抑制剂，IC50 值为 0.1063 μM。

AIMP2-DX2-IN-1 (Compound 35) is a potent AIMP2-DX2 inhibitor with an IC50 of 0.1063 μM.

AIMP2-DX2-IN-1 (Compound 35) (0-1 μM, 96 h) shows inhibitory activity against A549 and H460 cells without toxicity for normal cells.AIMP2-DX2-IN-1 showes very poor metabolic stability and good plasma stability in both human and mouse, and CYP inhibition need to be improved.Cell Viability Assay Cell Line:A549, H460 and WI-26 Concentration:0-1 μM Incubation Time:96 h Result:Showed inhibitory activities with EC50s of 0.690 ± 0.648 μM and 0.150 ± 0.062 μM against A549 and H460 cells, respectively. And is not active for WI-26.

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Others

Other Targets

Others

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848256-17-7

359.42

C23H21NO3

>98% (HPLC)

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C(NC(CC1=CC=C(C=C1)C2=CC=CC=C2)=O)C3OC=4C(OC3)=CC=CC4

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(-20℃)

With Ice Pack

≥ 2 years