021-51111890
购物车（）
sales@molnova.cn
PDD00017272
CAS No. 1945950-20-8
PDD00017272 ( —— )
产品货号. M35112 CAS No. 1945950-20-8
PDD00017272 (34f) 是有效的聚(腺苷二磷酸核糖)水解酶 (PARG) 抑制剂，其EC50 值分别为 4.8 nM 和 9.2 nM。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称PDD00017272
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述PDD00017272 (34f) 是有效的聚(腺苷二磷酸核糖)水解酶 (PARG) 抑制剂，其EC50 值分别为 4.8 nM 和 9.2 nM。
-
产品描述PDD00017272 (34f) is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with EC50 of 4.8 nM and 9.2 nM in biochemical assay and cell POM, respectively.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number1945950-20-8
-
分子量531.67
-
分子式C23H25N5O4S3
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO 中的溶解度 : ≥ 25 mg/mL (47.02 mM )
-
SMILESCc1ncc(Cn2c(=O)n(Cc3sc(C)nc3C)c3ccc(cc3c2=O)S(=O)(=O)NC2(C)CC2)s1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Bohdan Waszkowycz, et al. Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. J Med Chem. 2018 Dec 13;61(23):10767-10792.?
产品手册
关联产品
-
Neuropeptide SF (hum...
Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma.
-
Hypertrehalosaemic N...
Hypertrehalosaemic Neuropeptide, Heliothis zea
-
Orexin A (human, rat...
Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.
